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changes to reflect schema update 2.0.2
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lrdossan committed Jun 5, 2024
1 parent d25b41b commit 8524c3f
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Showing 4 changed files with 273 additions and 162 deletions.
2 changes: 1 addition & 1 deletion caimira/apps/calculator/model_generator.py
Original file line number Diff line number Diff line change
Expand Up @@ -208,7 +208,7 @@ def initialize_room(self) -> models.Room:
humidity = float(self.humidity)
inside_temp = self.inside_temp

return models.Room(volume=volume, inside_temp=models.PiecewiseConstant((0, 24), (inside_temp,)), humidity=humidity)
return models.Room(volume=volume, inside_temp=models.PiecewiseConstant((0, 24), (inside_temp,)), humidity=humidity) # type: ignore

def build_mc_model(self) -> mc.ExposureModel:
room = self.initialize_room()
Expand Down
4 changes: 2 additions & 2 deletions caimira/enums.py
Original file line number Diff line number Diff line change
@@ -1,5 +1,5 @@
from enum import Enum

class ViralLoads(Enum):
COVID_OVERALL = "Ref: Viral load - covid_overal_vl_data"
SYMPTOMATIC_FREQUENCIES = "Ref: Viral load - symptomatic_vl_frequencies"
COVID_OVERALL = "Ref: Viral load - covid overal viral load data"
SYMPTOMATIC_FREQUENCIES = "Ref: Viral load - symptomatic viral load frequencies"
90 changes: 55 additions & 35 deletions caimira/monte_carlo/data.py
Original file line number Diff line number Diff line change
Expand Up @@ -18,7 +18,7 @@ def evaluate_vl(root: typing.Dict, value: str, data_registry: DataRegistry):
if root[value] == ViralLoads.COVID_OVERALL.value:
return covid_overal_vl_data(data_registry)
elif root[value] == ViralLoads.SYMPTOMATIC_FREQUENCIES.value:
return symptomatic_vl_frequencies
return symptomatic_vl_frequencies(data_registry)
elif root[value] == 'Custom':
return param_evaluation(root, 'Viral load custom')
else:
Expand Down Expand Up @@ -66,11 +66,26 @@ def evaluate_custom_value_type(value_type: str, params: typing.Dict) -> typing.A
if value_type == 'Constant value':
return params
elif value_type == 'Normal distribution':
return Normal(params['normal_mean_gaussian'], params['normal_standard_deviation_gaussian'])
return Normal(
mean=params['normal_mean_gaussian'],
standard_deviation=params['normal_standard_deviation_gaussian']
)
elif value_type == 'Log-normal distribution':
return LogNormal(params['lognormal_mean_gaussian'], params['lognormal_standard_deviation_gaussian'])
return LogNormal(
mean_gaussian=params['lognormal_mean_gaussian'],
standard_deviation_gaussian=params['lognormal_standard_deviation_gaussian']
)
elif value_type == 'Uniform distribution':
return Uniform(params['low'], params['high'])
return Uniform(
low=params['low'],
high=params['high']
)
elif value_type == 'Log Custom Kernel distribution':
return LogCustomKernel(
log_variable=np.array(params['log_variable']),
frequencies=np.array(params['frequencies']),
kernel_bandwidth=params['kernel_bandwidth']
)
else:
raise ValueError('Bad request - value type not found.')

Expand Down Expand Up @@ -211,11 +226,7 @@ def activity_distributions(data_registry):

# From https://doi.org/10.1101/2021.10.14.21264988 and references therein
def symptomatic_vl_frequencies(data_registry):
return LogCustomKernel(
np.array(data_registry.virological_data['symptomatic_vl_frequencies']['log_variable']),
np.array(data_registry.virological_data['symptomatic_vl_frequencies']['frequencies']),
kernel_bandwidth=data_registry.virological_data['symptomatic_vl_frequencies']['kernel_bandwidth']
)
return param_evaluation(data_registry.virological_data, 'symptomatic_vl_frequencies')


# Weibull distribution with a shape factor of 3.47 and a scale factor of 7.01.
Expand All @@ -224,34 +235,34 @@ def symptomatic_vl_frequencies(data_registry):
def viral_load(data_registry):
return np.linspace(
weibull_min.ppf(
data_registry.virological_data['covid_overal_vl_data']['start'],
c=data_registry.virological_data['covid_overal_vl_data']['shape_factor'],
scale=data_registry.virological_data['covid_overal_vl_data']['scale_factor']
data_registry.virological_data['covid_overal_vl_data']['parameters']['start'],
c=data_registry.virological_data['covid_overal_vl_data']['parameters']['shape_factor'],
scale=data_registry.virological_data['covid_overal_vl_data']['parameters']['scale_factor']
),
weibull_min.ppf(
data_registry.virological_data['covid_overal_vl_data']['stop'],
c=data_registry.virological_data['covid_overal_vl_data']['shape_factor'],
scale=data_registry.virological_data['covid_overal_vl_data']['scale_factor']
data_registry.virological_data['covid_overal_vl_data']['parameters']['stop'],
c=data_registry.virological_data['covid_overal_vl_data']['parameters']['shape_factor'],
scale=data_registry.virological_data['covid_overal_vl_data']['parameters']['scale_factor']
),
int(data_registry.virological_data['covid_overal_vl_data']['num'])
int(data_registry.virological_data['covid_overal_vl_data']['parameters']['num'])
)
def frequencies_pdf(data_registry):
return weibull_min.pdf(
viral_load(data_registry),
c=data_registry.virological_data['covid_overal_vl_data']['shape_factor'],
scale=data_registry.virological_data['covid_overal_vl_data']['scale_factor']
c=data_registry.virological_data['covid_overal_vl_data']['parameters']['shape_factor'],
scale=data_registry.virological_data['covid_overal_vl_data']['parameters']['scale_factor']
)
def covid_overal_vl_data(data_registry):
return LogCustom(
bounds=(data_registry.virological_data['covid_overal_vl_data']['min_bound'], data_registry.virological_data['covid_overal_vl_data']['max_bound']),
bounds=(data_registry.virological_data['covid_overal_vl_data']['parameters']['min_bound'], data_registry.virological_data['covid_overal_vl_data']['parameters']['max_bound']),
function=lambda d: np.interp(
d,
viral_load(data_registry),
frequencies_pdf(data_registry),
data_registry.virological_data['covid_overal_vl_data']['interpolation_fp_left'],
data_registry.virological_data['covid_overal_vl_data']['interpolation_fp_right']
data_registry.virological_data['covid_overal_vl_data']['parameters']['interpolation_fp_left'],
data_registry.virological_data['covid_overal_vl_data']['parameters']['interpolation_fp_right']
),
max_function=data_registry.virological_data['covid_overal_vl_data']['max_function']
max_function=data_registry.virological_data['covid_overal_vl_data']['parameters']['max_function']
)


Expand All @@ -274,37 +285,43 @@ def virus_distributions(data_registry):
viral_load_in_sputum=evaluate_vl(vd['SARS_CoV_2'], 'viral_load_in_sputum', data_registry),
infectious_dose=param_evaluation(vd['SARS_CoV_2'], 'infectious_dose'),
viable_to_RNA_ratio=param_evaluation(vd['SARS_CoV_2'], 'viable_to_RNA_ratio'),
transmissibility_factor=vd['SARS_CoV_2']['transmissibility_factor'],
transmissibility_factor=vd['SARS_CoV_2']['transmissibility_factor']['value'],
infectiousness_days=vd['SARS_CoV_2']['infectiousness_days']['value'],
),
'SARS_CoV_2_ALPHA': mc.SARSCoV2(
viral_load_in_sputum=evaluate_vl(vd['SARS_CoV_2_ALPHA'], 'viral_load_in_sputum', data_registry),
infectious_dose=param_evaluation(vd['SARS_CoV_2_ALPHA'], 'infectious_dose'),
viable_to_RNA_ratio=param_evaluation(vd['SARS_CoV_2_ALPHA'], 'viable_to_RNA_ratio'),
transmissibility_factor=vd['SARS_CoV_2_ALPHA']['transmissibility_factor'],
transmissibility_factor=vd['SARS_CoV_2_ALPHA']['transmissibility_factor']['value'],
infectiousness_days=vd['SARS_CoV_2_ALPHA']['infectiousness_days']['value'],
),
'SARS_CoV_2_BETA': mc.SARSCoV2(
viral_load_in_sputum=evaluate_vl(vd['SARS_CoV_2_BETA'], 'viral_load_in_sputum', data_registry),
infectious_dose=param_evaluation(vd['SARS_CoV_2_BETA'], 'infectious_dose'),
viable_to_RNA_ratio=param_evaluation(vd['SARS_CoV_2_BETA'], 'viable_to_RNA_ratio'),
transmissibility_factor=vd['SARS_CoV_2_BETA']['transmissibility_factor'],
transmissibility_factor=vd['SARS_CoV_2_BETA']['transmissibility_factor']['value'],
infectiousness_days=vd['SARS_CoV_2_BETA']['infectiousness_days']['value'],
),
'SARS_CoV_2_GAMMA': mc.SARSCoV2(
viral_load_in_sputum=evaluate_vl(vd['SARS_CoV_2_GAMMA'], 'viral_load_in_sputum', data_registry),
infectious_dose=param_evaluation(vd['SARS_CoV_2_GAMMA'], 'infectious_dose'),
viable_to_RNA_ratio=param_evaluation(vd['SARS_CoV_2_GAMMA'], 'viable_to_RNA_ratio'),
transmissibility_factor=vd['SARS_CoV_2_GAMMA']['transmissibility_factor'],
transmissibility_factor=vd['SARS_CoV_2_GAMMA']['transmissibility_factor']['value'],
infectiousness_days=vd['SARS_CoV_2_GAMMA']['infectiousness_days']['value'],
),
'SARS_CoV_2_DELTA': mc.SARSCoV2(
viral_load_in_sputum=evaluate_vl(vd['SARS_CoV_2_DELTA'], 'viral_load_in_sputum', data_registry),
infectious_dose=param_evaluation(vd['SARS_CoV_2_DELTA'], 'infectious_dose'),
viable_to_RNA_ratio=param_evaluation(vd['SARS_CoV_2_DELTA'], 'viable_to_RNA_ratio'),
transmissibility_factor=vd['SARS_CoV_2_DELTA']['transmissibility_factor'],
transmissibility_factor=vd['SARS_CoV_2_DELTA']['transmissibility_factor']['value'],
infectiousness_days=vd['SARS_CoV_2_DELTA']['infectiousness_days']['value'],
),
'SARS_CoV_2_OMICRON': mc.SARSCoV2(
viral_load_in_sputum=evaluate_vl(vd['SARS_CoV_2_OMICRON'], 'viral_load_in_sputum', data_registry),
infectious_dose=param_evaluation(vd['SARS_CoV_2_OMICRON'], 'infectious_dose'),
viable_to_RNA_ratio=param_evaluation(vd['SARS_CoV_2_OMICRON'], 'viable_to_RNA_ratio'),
transmissibility_factor=vd['SARS_CoV_2_OMICRON']['transmissibility_factor'],
transmissibility_factor=vd['SARS_CoV_2_OMICRON']['transmissibility_factor']['value'],
infectiousness_days=vd['SARS_CoV_2_OMICRON']['infectiousness_days']['value'],
),
}

Expand All @@ -321,21 +338,24 @@ def mask_distributions(data_registry):
data_registry.mask_distributions['Type I'], 'η_inhale'),
η_exhale=param_evaluation(
data_registry.mask_distributions['Type I'], 'η_exhale')
if data_registry.mask_distributions['Type I'].get('η_exhale') is not None else None
if data_registry.mask_distributions['Type I'].get('η_exhale') is not None else None,
factor_exhale=data_registry.mask_distributions['Type I']['factor_exhale']['value']
),
'FFP2': mc.Mask(
η_inhale=param_evaluation(
data_registry.mask_distributions['FFP2'], 'η_inhale'),
η_exhale=param_evaluation(
data_registry.mask_distributions['FFP2'], 'η_exhale')
if data_registry.mask_distributions['FFP2'].get('η_exhale') is not None else None
if data_registry.mask_distributions['FFP2'].get('η_exhale') is not None else None,
factor_exhale=data_registry.mask_distributions['FFP2']['factor_exhale']['value']
),
'Cloth': mc.Mask(
η_inhale=param_evaluation(
data_registry.mask_distributions['Cloth'], 'η_inhale'),
η_exhale=param_evaluation(
data_registry.mask_distributions['Cloth'], 'η_exhale')
if data_registry.mask_distributions['Cloth'].get('η_exhale') is not None else None
if data_registry.mask_distributions['Cloth'].get('η_exhale') is not None else None,
factor_exhale=data_registry.mask_distributions['Cloth']['factor_exhale']['value']
),
}

Expand Down Expand Up @@ -399,8 +419,8 @@ def expiration_distributions(data_registry):
exp_type: expiration_distribution(
data_registry=data_registry,
BLO_factors=BLO_factors,
d_min=param_evaluation(data_registry.expiration_particle['long_range_expiration_distributions'], 'minimum_diameter'),
d_max=param_evaluation(data_registry.expiration_particle['long_range_expiration_distributions'], 'maximum_diameter')
d_min=param_evaluation(data_registry.expiration_particle['long_range_particle_diameter'], 'minimum_diameter'),
d_max=param_evaluation(data_registry.expiration_particle['long_range_particle_diameter'], 'maximum_diameter')
)
for exp_type, BLO_factors in expiration_BLO_factors(data_registry).items()
}
Expand All @@ -411,8 +431,8 @@ def short_range_expiration_distributions(data_registry):
exp_type: expiration_distribution(
data_registry=data_registry,
BLO_factors=BLO_factors,
d_min=param_evaluation(data_registry.expiration_particle['short_range_expiration_distributions'], 'minimum_diameter'),
d_max=param_evaluation(data_registry.expiration_particle['short_range_expiration_distributions'], 'maximum_diameter')
d_min=param_evaluation(data_registry.expiration_particle['short_range_particle_diameter'], 'minimum_diameter'),
d_max=param_evaluation(data_registry.expiration_particle['short_range_particle_diameter'], 'maximum_diameter')
)
for exp_type, BLO_factors in expiration_BLO_factors(data_registry).items()
}
Expand Down
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