DESCRIPTION

Package: dorothea
Type: Package
Title: Collection Of Human And Mouse TF Regulons
Version: 1.7.4
Authors@R: c(
    person(given = "Pau",
           family = "Badia-i-Mompel",
           role = c("cre"),
           email = "pau.badia@uni-heidelberg.de",
           comment = c(ORCID = "0000-0002-1004-3923")),
    person(given = "Daniel",
           family = "Dimitrov",
           role = c("aut"),
           email = "daniel.dimitrov@uni-heidelberg.de",
           comment = c(ORCID = "0000-0002-5197-2112")),
    person(given = "Christian H.",
           family = "Holland",
           role = c("aut"),
           email = "cholland2408@gmail.com",
           comment = c(ORCID = "0000-0002-3060-5786")),
    person(given = "Luz",
           family = "Garcia-Alonso",
           role = "aut"),
    person(given = "Alberto",
           family = "Valdeolivas",
           role = "ctb"),
    person(given = "Minoo",
           family = "Ashtiani",
           role = "ctb"),
    person(given = "Attila",
           family = "Gabor",
           role = "ctb")
           )
Description: DoRothEA is a gene regulatory network containing signed transcription factor (TF) - target gene interactions. DoRothEA regulons, the collection of a TF and its transcriptional targets, were curated and collected from different types of evidence for both human and mouse. A confidence level was assigned to each TF-target interaction based on the number of supporting evidence.
URL: https://saezlab.github.io/dorothea/, https://github.com/saezlab/dorothea
BugReports: https://github.com/saezlab/dorothea/issues
Depends: R (>= 4.0)
License: GPL-3 + file LICENSE
Encoding: UTF-8
LazyData: true
LazyDataCompression: xz
RoxygenNote: 7.2.3
VignetteBuilder: knitr
biocViews: ExperimentData, Homo_sapiens_Data, Mus_musculus_Data
Imports:
    dplyr,
    magrittr,
    bcellViper,
    decoupleR,
Suggests:
    Biobase,
    BiocStyle,
    OmnipathR,
    viper,
    knitr,
    pheatmap,
    pkgdown,
    rmarkdown,
    Seurat,
    SingleCellExperiment,
    SummarizedExperiment,
    testthat (>= 2.1.0),
    tibble,
    tidyr,
    utils